We focus on metabolic, inflammatory, and renal diseases with high unmet need

Learn about our clinical-stage candidates

INNOVATION IN METABOLIC SCIENCE

Transforming Treatment for Metabolic, Inflammatory, and Renal Diseases

We focus on metabolic, inflammatory, and renal diseases with high unmet need
We are a research-driven biopharmaceutical company developing innovative oral small-molecule therapies for obesity, chronic kidney disease (CKD), and inflammation-driven disorders. By uniting AI/ML discovery, medicinal chemistry, and translational biology, we design differentiated medicines and progress them efficiently through preclinical development toward first-in-human studies.

Our integrated AI/ML R&D platform accelerates target selection, molecule design, and de-risking, while our Biological Research Platform provides human-relevant in vitro/ex vivo systems and in vivo disease models to generate robust, decision-ready data. This end-to-end approach shortens the path from insight to candidate and keeps patient needs at the center of our work.

Backed by a collaborative network of partners and advisors, we are advancing a next wave of oral therapies aimed at reducing inflammation, restoring metabolic balance, and improving kidney health—to deliver meaningful outcomes for patients worldwide.

ADVANCING HUMAN HEALTH

Our Focus Areas

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We target chronic inflammatory processes that cause major health complications. Our programs span multiple pathways—including NLRP3, GPR75, and related nodes—and are built as brain-permeable or systemic candidates to match the biology.

Vector

Obesity

Comprehensive primary care services for overall health and well.

Kidney Disease

Specialized medical care for infants, children, and adolescents.

Sterile Inflammation

Advanced heart care services including diagnostics.

Neuroinflammation

Expert care for musculoskeletal conditions and injuries.

Cardiovascular

Comprehensive care for women's health and pregnancy.

Who We Are

Mwyngil is a biotechnology company founded in 2021. We grew out of a major scientific collaboration between Torrey Pines and DZNE (Deutsche Zentrum für Neurodegenerative Erkrankungen). From day one, we’ve built Mwyngil as a platform company—combining multiplex phenotypic assays with advanced computational approaches to modeling binding and selectivity to accelerate the translation of fundamental discoveries into clinical programs.

OUR TEAM

The People Behind Mwyngil

Our team unites leaders in biotechnology, medicine, and data science with a shared mission to translate groundbreaking biology into new therapies.

Nikolay Savchuk

PhD,
CEO

Vasily Kazey

PhD,
Head Pharmacology

Alexander Khvat

PhD,
Head MedChem

Claudia Filozof

MD PhD,
Head Clinical Development interim,
Endocrinology

Boris Rogovoy

PhD,
Head of Chemistry

Steph Mowery

PhD,
Head  Biology

Srini Natala

PhD,
Lead MedChem

Ruben Karapetyan

PhD,
Head Development

Iain Dukes

Venture Partner
OrbiMed, CEO

Nikolay Savchuk

PhD,
CEO

Eddie Wang Rodriguez

General Partner
Teal Ventures

Carl Gordon Chairman

General Partner
OrbiMed

Plamen Penev

MD PhD
Medical Affairs, Diabetes

Slava Gedulin

MD PhD

Louis Philipson

MD, PhD,
James C. Tyree Professor of Diabetes, UChicago

Prof Pierluigi Nicotera

MD, PhD
Scientific Director and Chairman of the Executive Board of DZNE, Advisor

Raghu Mirmira

MD, PhD, University of Chicago
Director of the Department of Med Translational Research Center

Investors

Empowered by our world-class investors, we advance the discovery and development of next-generation therapies for obesity, chronic kidney disease, and inflammatory disorders — united by a shared mission to improve patient lives globally.

CONTACT US

Contact with Mwyngil

Whether you’re exploring partnership opportunities or seeking information about our research, we’d be glad to hear from you.